Abstract

Reliable treatment effect estimation from observational data depends on the availability of all confounding information. While much work has targeted treatment effect estimation from observational data, there is relatively little work in the setting of confounding variable missingness, where collecting more information on confounders is often costly or time-consuming. In this work, we frame this challenge as a problem of feature acquisition of confounding features for causal inference. Our goal is to prioritize acquiring values for a fixed and known subset of missing confounders in samples that lead to efficient average treatment effect estimation. We propose two acquisition strategies based on i) covariate balancing (CB), and ii) reducing statistical estimation error on observed factual outcome error (OE). We compare CB and OE on five common causal effect estimation methods, and demonstrate
improved sample efficiency of OE over baseline methods under various settings. We also provide visualizations for further analysis on the difference between our proposed methods.

Abstract

Nonpharmaceutical interventions (NPIs) are the primary tools to mitigate early spread of the coronavirus disease 2019 (COVID-19) pandemic; however, such policies are implemented variably at the federal, provincial or territorial, and municipal levels without centralized documentation. We describe the development of the comprehensive open Canadian Non-Pharmaceutical Intervention (CAN-NPI) data set, which identifies and classifies all NPIs implemented in regions across Canada in response to COVID-19, and provides an accompanying description of geographic and temporal heterogeneity.

Abstract

Evolutionary and structural analyses of SARS-CoV-2 D614G spike protein mutation now documented worldwide

The COVID-19 pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), was declared on March 11, 2020 by the World Health Organization. As of the 31st of May, 2020, there have been more than 6 million COVID-19 cases diagnosed worldwide and over 370,000 deaths, according to Johns Hopkins. Thousands of SARS-CoV-2 strains have been sequenced to date, providing a valuable opportunity to investigate the evolution of the virus on a global scale. We performed a phylogenetic analysis of over 1,225 SARS-CoV-2 genomes spanning from late December 2019 to mid-March 2020. We identified a missense mutation, D614G, in the spike protein of SARS-CoV-2, which has emerged as a predominant clade in Europe (954 of 1,449 (66%) sequences) and is spreading worldwide (1,237 of 2,795 (44%) sequences). Molecular dating analysis estimated the emergence of this clade around mid-to-late January (10–25 January) 2020. We also applied structural bioinformatics to assess the potential impact of D614G on the virulence and epidemiology of SARS-CoV-2. In silico analyses on the spike protein structure suggests that the mutation is most likely neutral to protein function as it relates to its interaction with the human ACE2 receptor. The lack of clinical metadata available prevented our investigation of association between viral clade and disease severity phenotype. Future work that can leverage clinical outcome data with both viral and human genomic diversity is needed to monitor the pandemic.

Abstract

TAFA: Two-headed Attention Fused Autoencoder for Context-Aware Recommendations

Collaborative filtering with implicit feedback is a ubiquitous class of recommendation problems where only positive interactions such as purchases or clicks are observed. Autoencoder-based recommendation models have shown strong performance on many implicit feedback benchmarks. However, these models tend to suffer from popularity bias making recommendations less personalized. User-generated reviews contain a rich source of preference information, often with specific details that are important to each user, and can help mitigate the popularity bias. Since not all reviews are equally useful, existing work has been exploring various forms of attention to distill relevant information. In the majority of proposed approaches, representations from implicit feedback and review branches are simply concatenated at the end to generate predictions. This can prevent the model from learning deeper correlations between the two modalities and affect prediction accuracy. To address these problems, we propose a novel Two-headed Attention Fused Autoencoder (TAFA) model that jointly learns representations from user reviews and implicit feedback to make recommendations. We apply early and late modality fusion which allows the model to fully correlate and extract relevant information from both input sources. To further combat popularity bias, we leverage the Noise Contrastive Estimation (NCE) objective to “de-popularize” the fused user representation via a two-headed decoder architecture. Empirically, we show that TAFA outperforms leading baselines on multiple real-world benchmarks. Moreover, by tracing attention weights back to reviews we can provide explanations for the generated recommendations and gain further insights into user preferences.

Abstract

ACM RecSys Challenge 2020

Twitter has become one of the main information sharing platforms for millions of users world-wide. Numerous tweets are created daily, many with highly time sensitive content such as breaking news,
new multimedia content or personal updates. Consequently, accurately recommending relevant tweets to users in a timely manner is a highly important and challenging problem. The 2020 ACM RecSys
Challenge is aimed at benchmarking leading recommendation models for this task. The challenge is based on a large and recent dataset of over 200M tweet engagements released by Twitter with content in over 50 languages. In this work we present our approach where we leverage recent advances in deep language modeling and attention architectures, to combine information from extracted features, user engagement history and target tweet content. We first fine tune leading multilingual language models M-BERT and XLM-R for Twitter data. Embeddings from these models are used to extract tweet and user history representations. We then combine all components together and jointly train them to maximize engagement prediction accuracy. Our approach achieves highly competitive performance placing 2’nd on the final private leaderboard.